Antagonistic regulation of LINE-1/Alu elements and their repressor APOBEC3B in cellular senescence
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Long Interspersed Nuclear Elements-1 (LINE-1 or L1) make up approximately 21% of the human genome, with some L1 loci containing intact open reading frames (ORFs) that facilitate retrotransposition. Because retrotransposition can have deleterious effects leadin... ...
