Based on multi-pathway induction of tumor immunogenic death and three-mode highly integrated strategy: a nanocomposite system loaded with irinotecan for colorectal cancer therapy
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Irinotecan (CPT-11), a first-line chemotherapeutic agent for colorectal cancer, faces challenges like tumor drug resistance and severe toxicities such as neutropenia and diarrhea. Current nanocarriers for CPT-11 have limitations in achieving high drug loading ... ...