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Combined non-myeloablative total lymphoid irradiation and low-dose total body irradiation enhances donor chimerism and leads to islet allograft acceptance

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The non-myeloablative conditioning regimen comprising total lymphoid irradiation (TLI) and anti-thymocyte globulin (ATG) is used for allogeneic hematopoietic stem cell transplant patients. There is a need to safely intensify TLI+ATG to allow for the achievemen... ...