Pedigree analysis and genetic inheritance of fatal familial insomnia (FFI) in a Portuguese multigenerational family
{{output}}
Fatal familial insomnia (FFI) is a rare, autosomal dominant prion disease caused by a mutation in the PRNP gene, leading to the misfolding of the cellular prion protein (PrPC) into its pathogenic form (PrPSc). This results in neurodegeneration, particularly in... ...
