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Inhibiting mPGES-2 impedes renal cyst growth in mice with polycystic kidney disease

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Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of multiple fluid-filled cysts in the kidneys, resulting in progressive decline and failure of renal function. Microsomal prostaglandin E synthase-2 (mPGES-2) is a unique ... ...