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Formation of CO2-dependent small-colony variants (SCVs) in methicillin-resistant Staphylococcus aureus mediated by a single point mutation in mpsB

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Introduction: Staphylococcus aureus is a major human pathogen and the emergence of small colony variants (SCVs) makes the treatment of S. aureus infections more challenging. The mechanism of CO2-dependent SCVs (CO2-SCVs) remains ... ...