Variable response of germline activating PDGFRB variants to receptor tyrosine kinase inhibitors: implications for treatment
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Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase that plays significant roles in cell growth, proliferation, and differentiation. Germline variants of PDGFRB can lead to several different diseases, e.g. infantile myofibromat... ...
