Design, synthesis and anti-breast tumor activity of Berberine hydrogen sulfide donor derivatives
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In order to improve the antitumor activity of berberine, different hydrogen sulfide donors were synthesized by alkyl chain splicing berberine isoquinoline. The total of 33 new compounds were synthesized. It showed that ber-a5, ber-a8 and ber-b5 had strong inhi... ...
