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Age-specific tumor-associated macrophage biomarkers underlie metastasis and immune dysregulation in thyroid cancer

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Thyroid cancer (THCA) shows rising incidence and aggressiveness in young-onset cases. Through integrated single-cell, transcriptomic, and proteomic analyses, we identified age-specific tumor-associated macrophage (TAM) genes, including OLR1 and SIGLEC1, linked... ...