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DNA-hypermethylated human gastric cancer circumvents apoptosis in the absence of TP53 mutation

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p53 is one of the most important tumour suppressors exerting antitumour effects primarily via apoptosis. TP53 mutations are common in gastric tumorigenesis; however, nearly half of the gastric cancers (GCs) remain wildtype TP53 (TP53_WT). We investigated epige... ...