Senataxin regulates cisplatin resistance through an R-loop-mediated mechanism in HPV-associated head and neck cancer
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Resistance to cisplatin is a key clinical concern in HPV-independent (HPV-) and HPV-associated (HPV+) head and neck cancer. Upregulation of DNA repair is known to contribute to cisplatin resistance and a major source of endogenous DNA damage are DNA/RNA hybrid... ...
