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Astragalus polysaccharide-based nano-platforms loading PTX to boost chemo-immunotherapy for triple-negative breast cancer with intrinsic GLUT-targeting ability and immunoregulatory activity

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Chemo-immunotherapy shows great promises for triple-negative breast cancer (TNBC) treatment, including PTX. However, the chemo-immunotherapy of PTX is limited, due to its upregulation of PD-L1 expression on tumor cells and bone marrow suppression. In addition,... ...