Hepatic protein kinase Cbeta antagonizing p38MAPK to activate ERK1/2 to dysregulate biliary lipid composition upon lithogenic stress
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Lithogenic diet exposure disrupts biliary lipid homeostasis to promote precipitation of excess biliary cholesterol; however, the underlying pathogenic signaling mechanism remains unclear. Protein kinase Cbeta (PKCβ) is involved in regulating hepatic cholester... ...
