Spheres, worms, and packing problems in the nanoscale assembly of ALS-linked protein Matrin-3
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Matrin-3 (MATR3) is an RNA-binding protein that forms higher-order assemblies and pathological inclusions associated with neurodegenerative diseases. In this issue of Molecular Cell, Sprunger et al.1 explore the assembly of MATR3 and find that it forms spheric... ...