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Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation

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Insulin-like growth factor-2 receptor (IGF2R), also known as cation-independent mannose-6-phosphate receptor, is localized in cytosolic vesicles and is unique in its ability to transport enzymes to the lysosome and to clear IGF2 from the cell surface by acting... ...