Reduced insulin-like signaling restores motor and chemosensory neuron function in C. elegans expressing TDP-43, an ALS-associated protein
{{output}}
TAR DNA-binding Protein 43 (TDP-43) is linked to the pathology of neurodegenerative diseases. We used the roundworm Caenorhabditis elegans to examine the neurotoxic impact of the pan-neuronal expression of wild-type human TDP-43 (hTDP-43) fused to a yellow flu... ...
