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HMGCR genetic variability in Parkinson's disease in a Spanish cohort: associations with lipid metabolism and early onset

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Lipid metabolism has emerged as a key factor in the pathophysiology of Parkinson's disease (PD). While 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme in cholesterol biosynthesis, has been implicated in neurodegenerative diso... ...