Altered gut microbiota mediates the association between APOE genotype and amyloid-β accumulation in middle-aged adults
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Background: The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for Alzheimer's disease, yet the mechanisms linking APOE to amyloid-β (Aβ) pathology remain incompletely understood. Emerging evidence sug... ...
