Distinct impacts of human co-chaperone UNC45 paralogues on Drosophila muscle development and function
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Uncoordinated-45 (UNC45) is a conserved protein required for myosin accumulation during muscle development. Invertebrates have one unc-45 gene whereas vertebrates have two paralogues, UNC45A and UNC45B, which exhibit differential expression patterns. We used t... ...