Impact of naturally occurring hemagglutinin substitutions on antigenicity and fitness of influenza A(H5N1) virus
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In 2024, a human infection with clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) virus was identified in the United States in an individual with no known exposure. Genetic analysis revealed two hemagglutinin (HA) substitutions, P136S and A156T, which m... ...
