Choline hydroxide mediated eco-friendly synthesis of 5-arylidene thiazol-4(5H)-one clubbed coumarin: antimicrobial evaluation and in silico studies
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An efficient and eco-friendly method was developed for synthesizing coumarin-thiazolidinone hybrids using choline hydroxide as a green catalyst. A series of arylidene derivatives (3a-i, 5) were prepared and characterized. Antimicrobial screening against Gram-p... ...