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A centenarian single nucleotide polymorphism in collagen gene COL25A1 promotes longevity in C. elegans

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Before human genome sequencing, a genome-wide study of sibling centenarian pairs identified a longevity-associated locus on chromosome 4. Here, we mapped the genes in this locus and identified a collagen gene, COL25A1. Introducing an SNP linked to longevity th... ...