Conventional and alternative approaches for targeting PIK3CA and PTEN alterations in head and neck, breast, and other cancers
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Genetic alterations in genes encoding components of the PI3K/AKT/mTOR signaling pathway are frequently observed in head and neck squamous cell carcinoma (HNSCC), breast cancer, and a variety of other human malignancies. In particular, PIK3CA, encoding the p110... ...
