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Pro-angiogenic potential of the isoxazole derivative ISO-1 via α7-nAChRs activation in human endothelial cells

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Angiogenesis is essential for tissue growth and repair, but its dysregulation is associated with various pathological conditions, such as cancer and ischemic disease. Non-neuronal α7-nicotinic acetylcholine receptors (α7-nAChRs) mediate angiogenic pathways. ... ...