Selenium nanoparticles alleviate cobalt toxicity in artificial joint metal prostheses by inhibiting ferroptosis through activation of the PRDX6/GPX4 pathway
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The long-term implantation of metallic joint prostheses results in the release of cobalt nanoparticles (CoNPs), leading to local and even systemic toxic reactions that pose risks to patient health. Previous studies have suggested that CoNPs-induced cytotoxicit... ...
