HDAC6 as a Modulator of DNA Repair in Alzheimer's Disease: From Mechanisms to Therapeutic Perspectives
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Double-strand breaks (DSBs) are the most cytotoxic DNA damages that arise from endogenous processes (oxidative metabolism as well as external stressors); unrepaired DSBs are consistently found in the hippocampus and cortex of Alzheimer's disease (AD) brains a... ...