Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS)
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Background and objectives: Induction of PGC1α/oxidative phosphorylation (OXPHOS) is associated with disease progression and treatment resistance in cutaneous melanoma patients. Loss of the TET2/5-hydroxymethylcytosine (5-hmC) ep... ...
