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Neuromyotonia and CASPR2 Antibodies: Electrophysiological Clues to Disease Pathophysiology

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Contactin-associated protein-like 2 (CASPR2) is a transmembrane protein of the neurexin superfamily, essential for clustering voltage-gated potassium channels, particularly Kv1, at the juxtaparanodal regions of myelinated axons. This precise localisation is es... ...