Human astrocytes from healthy individuals and Alzheimer's patients respond differently to Aβ1-42 oligomers, triggering distinct paths of reactivity and senescence
{{output}}
Alzheimer's disease (AD) is a neurodegenerative disorder characterised by cognitive decline, amyloid-β (Aβ) plaques, and neurofibrillary tangles. Aβ1-42 oligomers exert neurotoxic and pro-inflammatory effects. Astrocytes maintain brain homeostasis, and the... ...