Polymer-engineered liposome-delivered Ebselen against tumor through GSH/H2O2-responsive disruption of redox homeostasis and direct p53 activation
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Ebselen (EbSe), an organic selenium-based compound with potential antitumor activity, faces great challenges of poor aqueous solubility, which impairs its bioavailability and exacerbates potential toxicity. Liposomes, as established clinical tools for deliveri... ...