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Design and optimization of carvedilol-loaded transbilosomes for the control of diabetic high-fat diet-induced atherosclerosis in rats

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Objectives: Carvedilol (CDL) is an oral beta-adrenergic blocker known for enhancing arterial blood flow and reducing hyperglycemia due to its antioxidant properties. However, CDL's short half-life leads to its low efficacy and p... ...