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The Potential of Microwave Radiation and Mechanochemistry in the Formation of Purine Alkaloids Cocrystals Using Pyromellitic Acid as a Coformer: Synthesis, Structural, Spectroscopic, Thermal Analysis, and Biological Properties

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Cocrystallization provides an efficient approach to modifying a wide range of physicochemical properties of active pharmaceutical ingredients (APIs), including solubility, dissolution rate, melting point, and hygroscopicity. Therefore, the development of effec... ...