High mobility group box 1 attenuates aortic stenosis by modulating macrophages to reduce valvular calcification
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Our previous study demonstrated that HMGB1 may suppress M1 macrophage polarisation and mitigate the progression of calcific aortic valve disease (CAVD). However, the role of HMGB1 in regulating macrophage-mediated valvular calcifi-cation remains to be further ... ...