Modeling Midbrain and Brainstem Neuromelanins to Characterize Metal Binding and Associated MRI Contrast in Parkinson's and Alzheimer's Diseases
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Neuromelanin (NM) is a dark pigment that binds potentially toxic metal ions and is crucial for neuronal vulnerability. Magnetic resonance imaging (MRI) was proposed to measure neuromelanin in the substantia nigra or locus coeruleus, potentially providing a mar... ...
