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Molecular-Level Insights into TIMS-MS Separation of α/β-Estradiol Isomers: Synergistic Effects of Cyclodextrins and Metal Ions

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This study presents a novel approach for the rapid and high-resolution separation of estrogen isomers (α/β-estradiol and estriol: α/β-E2/E3) using trapped ion mobility mass spectrometry (TIMS-MS). Systematically, evaluating cyclodextrin (α-, β-, and γ-C... ...