Flash Communication: Ti-Catalyzed "Interrupted" Cascading Hydroamination of 1,6- and 1,7-En-ynes
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Herein, we report a new hydroaminative cyclization for 1,6 and 1,7 en-ynes using a simple Ti imido precatalyst, [py2TiCl2(NPh)]2. The well-known Ti imido + alkyne [2+2] azatitanacyclobutadiene cycloadduct intermediate can be further intercepted via insertion b... ...
