RhoGEF2 overexpression induces cell competition dependent on Ptp10D, Crumbs, and the Hippo signaling pathway
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In Drosophila melanogaster larval epithelial tissues, cells containing mutations in the apico-basal polarity protein, Scrib, are eliminated by cell competition when surrounded by wild-type cells. In scrib mutant cells, signaling mediated by the receptor-type t... ...