Single-Cell RNA Analysis Reveals Reduced Frequency and Activity of CXCR5+ Atypical Memory B Cells in Islet Xenotransplantation Treated With Clinically Applicable Immunosuppressants Including Belimumab
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Background: Porcine-to-human islet xenotransplantation offers a promising solution to type 1 diabetes. This study investigates the use of Belimumab, a human monoclonal antibody that inhibits B cell activating factor (BAFF) as par... ...
