Apobec3 shows rapid evolution in house mouse subspecies and unusual hypermutation patterns of endogenous mouse mammary tumor viruses
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Apobec3 (A3, apolipoprotein B editing complex 3) is a cytidine deaminase with broadly antiretroviral activity. A3 is packaged in virions and converts cytidines to uracil (C > U) in viral minus-strand DNA during reverse transcription, resulting in guanosine to ... ...
