Dual-Enzyme Encapsulated Porous Nanocapsules for Lysosome-Targeted, Hypoxia-Amplified Cancer Therapy
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Glucose oxidase (GOx) catalyzes the oxidation of glucose to gluconic acid and hydrogen peroxide (H2O2), while horseradish peroxidase (HRP) converts H2O2 into cytotoxic hydroxyl radicals (•OH) under acidic conditions, such as those in lysosomes. Harnessing thi... ...