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Developing an AI-Generated Peptide Targeting Platelet-type von Willebrand Disease

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Platelet-type von Willebrand disease (PT-VWD) is a rare bleeding disorder caused by gain-of-function mutations in platelet glycoprotein Ib alpha (GPIbα). These mutations lead to a hyperactive protein-protein interaction (PPI) with von Willebrand factor (VWF) ... ...