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Case Report: Relapsed alveolar rhabdomyosarcoma treated with abemaciclib, temozolomide, and irinotecan in the JPCS study

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Background: Cyclin-dependent kinase (CDK) 4 and CDK6 play fundamental roles in cell cycle progression. The CDK4/6 inhibitor abemaciclib, in combination with temozolomide and irinotecan, was evaluated in pediatric and young adult ... ...