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Discovery of Novel Hydroxyproline-Containing Microcystins in Western Lake Erie Cyanobacterial Bloom Samples

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From midsummer to fall, cyanobacterial harmful algal blooms (cHABs) producing microcystins (MCs), a class of hepatotoxic cyclic heptapeptides, plague Lake Erie's western basin. Since MC congener toxicities vary over 2 orders of magnitude, identification and c... ...