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SerpinE2 deficiency exacerbates glomerular Injury in diabetic nephropathy through dysregulated angiogenesis and inflammatory responses

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Diabetic nephropathy (DN) is a multifactorial disease in which inflammation and angiogenesis play a crucial role. SerpinE2, or protease nexin-1 (PN-1), is a protease inhibitor of the serpin family, expressed by vascular and inflammatory cells. In this study, w... ...