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The simultaneous activation of μ- and δ-opioid receptors by (-)-2 S-LP2 rescues allodynia with the contribution of TGF-β1 signaling in a rat chronic constriction injury model

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In neuropathic pain (NP), a dysregulation of glial functions in the central and peripheral nervous systems has been described, and the balance between pro-inflammatory and anti-inflammatory mediators is lost in the transition from acute to chronic pain. This r... ...