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The non-canonical thioreductase Tmx2b is essential for neuronal survival during zebrafish embryonic brain development

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Biallelic variants in thioredoxin-related transmembrane 2 protein (TMX2) can cause a malformation of brain cortical development characterized by microcephaly, polymicrogyria and pachygyria by an unknown mechanism. To investigate and visualize how TMX2 loss dis... ...