The key enzyme PYCR1 in proline metabolism: a dual driver of cancer progression and fibrotic remodeling
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Pyrroline-5-Carboxylate Reductase 1 (PYCR1), a member of the PYCR family, is a key enzyme in the proline biosynthesis pathway. Notably, PYCR1 was originally identified via genetic disease research, linking its mutations to the occurrence of cutis laxa. PYCR1 c... ...