Hepatotoxicity of 8:2 Polyfluoroalkyl Phosphate Diesters Exposure via JAK2/STAT3 Pathway Activation and M1 Macrophage Polarization in Mice
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Polyfluoroalkyl phosphate esters (PAPs) are widely used as substitutes for legacy perfluoroalkyl and polyfluoroalkyl substances (PFAS), contributing a non-negligible environmental burden. However, their in vivo hepatotoxicity and underlying mechanisms remain p... ...
