Understanding the Effect of Surface-Grafted Polyethylene Glycol Chains on Scavenger Endothelial Cell Sequestration of Polymeric Nanoparticles via Quantitative Pharmacokinetic Analysis in Zebrafish Larvae
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Scavenger endothelial cells (SECs) lining the liver sinusoids play a critical role in the rapid blood clearance of nanoparticle (NP)-based drug-delivery systems. However, how these cells recognize synthetic materials is largely unknown, which hampers the estab... ...
