Neurons ensheathed by perineuronal nets are prone to hyperphosphorylation of tau protein in the hibernating Syrian hamster brain
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Perineuronal nets (PNNs) are a specialized form of neuronal extracellular matrix that often ensheath highly active cells, such as parvalbumin-positive (PV+) interneurons. Net-bearing neurons have been shown to be devoid of pathological aggregates of hyperphosp... ...